Adobe Apollo
Apollo is the code name for a cross-operating system runtime that allows developers to leverage thier existing Web development skills in HTML, JavaScript, AJAX, Flash, and Flex in order to build and deploy rich Internet applications (RIAs) to the desktop. Apollo applications can engage audiences anywhere, anytime, allowing users to interact with RIAs, to experience interactive media and to collaborate on information and documents outside the constraints of the browser.
http://labs.adobe.com/wiki/index.php/Apollo